Morphologic and ultrasound survey in type 2 diabetic placenta
A. Tetileanu, C. Berceanu, E. Brătilă, D. Navolan, R. Ciortea, S. Berceanu, M. Cîrstoiu, A. Ofițeru, R. Bohîlțea, A. Stepan, C. Mehedințu
Abstract: The aim of this study is to establish morphological, histological and ultrasonographic (US) correlations in the placenta
of type 2 diabetes. This is a multicenter case-control study conducted on a lot of 21 selected cases diagnosed with type 2
diabetes, analyzed over a two year period. The clinical characteristics of the patients in the study group are represented
by the average age of 34 years and diabetes associated with preeclampsia, hypertension, diabetic neuropathy, urinary
infections, obesity or history of infertility. All the patients in the study group are Caucasian. US assessment of placental
characteristics in our series revealed increased placental thickness from the second trimester and placentomegaly at the end
of the third trimester. Immature appearance of placenta has been observed. Gross analysis of maternal and fetal surfaces
of the placentas revealed basal plate and subchorionic fibrin depositions, placental infarction or intervillous thrombosis.
Preconceptional glycemic control and its support during gestation are essential for pregnancy outcome. US findings have
as a background the morphological changes. From morphological perspective there is about a combination of anomalies,
otherwise unspecific which, in terms of association with various comorbidities could define a placental diabetic pattern.
DOI:10.18643/gieu.2018.5