DOI:10.18643/gieu.2018.49
"> DOI:10.18643/gieu.2018.49
"> DOI:10.18643/gieu.2018.49
"/> Nifedipine side effects during the first 48 hours of premature labour treatment and their treatment impact in the maternal foetal outcome
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GINECOeu14(2)49-51(2018)
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Nifedipine side effects during the first 48 hours of premature labour treatment and their treatment impact in the maternal foetal outcome

A. Karameta


Abstract: Nifedipine is the first line tocolytic agent used in tocolytic protocols of University Hospital for Obstetrics & Gynaecology “Koco Gliozheni” from Albania for 9 years. It has a good tocolytic effect, fewer adverse and side effects compared to other tocolyticagents, easy way of administration and low cost. During our study period we randomly created groups from 480 total patients: the 1st group (n=280) applied nifedipine tocolysis; the 2nd group (n=200), patients pre-advised about nifedipine side effects and the 3rd group (n= 45) included patients of the 1st group that interrupted nifedipine tocolysis because of its side effects, but reentered in therapy after being advised about the importance of premature labour treatment and the ways to treat nifedipine side effects. About 7 patients who discontinuated nifedipine tocolysis for its side effects, after being supported psychologically, treated with fluid regimen and medicaments to relief the simptoms, underwent successfully to the nifedipine tocolysis. In the present study, all the patients who were psychologically prepeared to experience the nifedipine side effects and used fluid diet regimen, experienced less and lighter side effects. Vital signs profile monitoring is very important for a safe treatment. Nifedipine side effects detection/observation and treatment is very important for the successful treatment of premature labour, especially for a better outcome of both mother and foetus.
DOI:10.18643/gieu.2018.49

Keywords: nifedipine, premature labour, side effects, treatment.

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