Correlations between Babes-Papanicolaou’s findings and immunosuprression in Human Immunodeficiency Virus infected women

S. Halichidis, S. C. Cambrea, G. Resul, L. Mocanu, I. Costandache, N. Ceamitru, O. C. Arghir

Abstract: To assess the frequency and correlations between immunosupression and cytological findings of Babes-Papanicolaou test in HIV infected women. Methods. Prospective study from January, the 1st 2011 to April, the 30th 2013, in the Clinical Infectious Hospital, Constanta, Romania, included 98 HIV infected women, 92.9% highly active antiretroviral therapy (HAART) recipients, who inform consented to Babes-Papanicolaou technique. Immunologic data were correlated with cervical cytological smears results, classified by 2001 Bethesda System. Descriptive and bivariate statistics were performed using SPSS version 17. Results. 41.83% of HIV infected females (n=41/98), mean aged 27.65 +/- 7.690 y.o. (limits: 15-60 years), 73.58% HAART recipients (n=39/53), presented abnormal results of cervical cytology. The risk of squamous cell lesions (SILs) is increased when CD4 cell counts are decreased.
DOI:10.18643/gieu.2013.122

Keywords: HIV, squamous intraepithelial lesions, Babes-Papanicolaou cervico-vaginal smear, HPV, HAART