The prognostic value of hemoglobin level in cervical cancer patients

J. J. Gmyrek, A. Z. Siwinska, L. Gmyrek

Abstract: The present paper aim to assess the prognostic value of pretreatment hemoglobin (Hb) level in cervical cancer patients. A number of 142 adenocarcinoma (AC) and 242 squamous cell cancer (SCC) patients, FIGO stage I-IVA, treated with surgery and radiotherapy (RT) or RT alone, were analyzed retrospectively. Factors as the pretreatment Hb level, FIGO stage, the tumor diameter, the histopathology, and WHO status were analyzed. As the cut-off value of Hb level, 10 g/dl and 13 g/dl was accepted. Independently of the other factors, the pretreatment Hb level in cervical SCC patients had statistically significant association with overall survival (OS) (p=0.031) and disease free survival (DFS) (p=0.019). In patients with AC, Hb level was not statistically significant for OS (p=0.58) and DFS (p=0.29). The pretreatment Hb concentration in patients with SCC of the uterine cervix seems to be an important prognostic factor.
DOI:10.18643/gieu.2015.84

Keywords: cervical cancer, hemoglobin level, prognostic factors, treatment results.