Abstract: Endometrial cancer is the most common gynecologic malignancy in developed countries, with an average incidence of
14.7/100,000 women and ranks second place after cervical cancer in developing countries, with an average incidence
of 5.5/100,000. The global average incidence in 2012 was 8.2/100,000 women, representing 319 605 cases of cancer of
the endometrium. The reported incidence in 2012 of cancer of the endometrium for Romania was 8.46/100000 women,
within Europe the same year average was 13.6/100,000 women. In Romania, pick the incidence occurs in the age group
60-64 years (42.8/100,000 women), the cumulative risk being 1%. According to World Health Organization predictive
estimates for Romania is expected for 2015 an increase in the number of new cases by 2.92% to 10.07% for 2025 and
for 2035 with 15.33%, of whom, under the age of 65 years in 2015 will be 990 new cases, in 2025 will be 986 new cases
and in 2035 under this age will be 1027 new cases of cancer of the endometrium. The data for the period 2005-2015 was
investigated coming from reports of family doctors, the national registry for cancer and (SIUI). Of the total of admissions
for diagnosed endometrial cancer, 10% have affected women under 50 years, and 2.78% women under 40 years. Studying
the National Registry for Cancer for 2005-2007, regarding new cases reported by district oncology cabinets, an average
number of 108 new endometrial cancer cases/year has resulted and respectively 237 new colorectal cancer cases for
women under 50. The total number is significant, representing the patients whose genetic testing is essential for defining
an important high risk group for familial cancer, a fact that is universally accepted, the screening which is intended for.
DOI:10.18643/gieu.2016.15