The occurrence of the ureterohydronephrosis in advanced genital cancers in Romanian women: a small cohort study in Arad County Clinical Hospital

C. Para, I. Ioiart, V. Dascau

Abstract: Cervical and ovarian neoplasia are important causes of cancer-related mortality. Both are routinely associated with uretrohydronephrosis (UHN) an inflammation - induced dilatation of the urinary collecting system of the kidney. The purpose of this article is to identify the incidence and stage of these cancers and related UHN in a cohort of 43 patients from the Arad County Clinical Hospital. The relationships among them, as well as those with the patient current age, its age at diagnosis of neoplasia, the time after the initial diagnosis and residence area (rural vs. urban) were also analyzed. The mean age of occurrence of neoplasia was 55.85 years. We found a higher incidence of these cancers in rural areas than in urban areas. Most patients were in advanced stages (grade III, IV, and V), with only three being in stage II. UHN commonly accompanied these cancers and was found especially on the right side. There were significant associations between the residence area and the prevalence of bilateral UHN and unilateral left UHN. The unilateral right UHN, but not the unilateral left UHN, correlated directly with both the ovarian and cervical neoplasias. Therefore, we suggest that the implementation of specific rural national programmes for the screening and early diagnosis of ovarian and cervical cancer and their urinary complications should focus on patients 50 years or higher and consider the residence area as a potential factor influencing the incidence of these neoplasias.
DOI:10.18643/gieu.2016.71

Keywords: women, genital cancer, cervix, ovary, ureterohydronephrosis.