T.L. Hangan, D. Badiu, S. Vlădăreanu, D. Navolan, C.A. Ionescu
Abstract: The transition made by the newborn when pass through intra-uterine medium to a new world, will determinate
new changes of the immune system against harmful environment. These changes can renders newborns to many
pathogens which could lead to some pathologies like pre-term delivery. The immune system works with adaptive
immunity response which requires previous contact with antigens and with innate system response without
requiring immune experience. Therefore, a better understanding of the cell mechanisms of the immune system
which start to develop from newborn to childhood and then adulthood will help physicians to improve the sites
of different infections during this period of life. This review focuses mainly on the role of T and B-cells activation
in newborns, innate and adaptive immunity, and the changes from newborn to childhood and adulthood.
DOI:10.18643/gieu.2017.123