Mild stimulation versus conventional ovarian stimulation in a cohort of poor responders

N. A. Krayem, M. Braila, A. C. Velisu, M. Cosma, A. Braila

Abstract: Much attention is being directed nowadays toward individualized medicine. Worldwide clinicians use different types of protocols for ovarian stimulation during human assisted reproduction techniques. In the last few years, researchers have tried to find the most appropriate stimulation protocol taking into consideration the ovarian response, clinical outcome, cost and complications. Mild stimulation has been proposed for patients with poor ovarian response, instead of the conventional protocol, because of its better safety profile and reduced costs. We studied 92 patients with poor ovarian response that underwent procedures in the department of Human Assisted Reproduction of Clinical Hospital of Obstetrics and Gyneacology “Prof. Dr. Panait Sârbu” from Bucharest, Roamnia between between January 2015 and June 2017. Our goal was to compare the outcomes of the procedures in patients that received conventional protocol or mild stimulation. The results favored the conventional protocol in terms of number of oocytes retrieved but showed no difference in terms of β-human chorionic gonadotropin positivity, clinical pregnancy rate and abortion rate.
DOI:10.18643/gieu.2018.58

Keywords: poor ovarian response, mild stimulation, conventional ovarian stimulation, clinical pregnancies.